At the MVP summit last year I picked up a Sculpt Ergonomic Desktop pack, mainly because I cannot stand the UK keyboard layout and wanted to stay on the US layout while working in London.
I just had a very strange issue, I could not type a capital V, lowercase worked fine. Plugging into another machine showed the same issue.
One of the problems with the Sculpt is that the function keys get stuck. Apparently if the
F5 key gets stuck, then you can no longer type a capital V. If the
F2 key is stuck then you won’t be able to type a capital C.
If you hit this random issue, hopefully you will read this post before returning your keyboard.